I think DBMan would be able to handle your database.

There are ways to cut down on the amount of fields needed by creating select fields. That way each and every option would not necessarily need it's own field in some cases.

You could also look into using the relational mod and using a few databases working together.

Did you by any chance search for "hotel" to see if you could find other posts relating to this type of database. You might find some good ideas.